Clinical-stage biotechnology company, Bolt Biotherapeutics, Inc. (BOLT Quick QuoteBOLT ) has entered into a clinical collaboration and supply agreement with biotech giant, Bristol Myers (BMY Quick QuoteBMY ) .
Per the agreement, Bolt will evaluate its pipeline candidate BDC-1001 in combination with Bristol Myers immuno-oncology drug Opdivo.
Bolt’s lead candidate, BDC-1001, is a Boltbody ISAC comprising a HER2-targeting biosimilar of trastuzumab conjugated with a non-cleavable linker to one of Bolt’s proprietary TLR7/8 agonists for the treatment of patients with HER2-expressing solid tumors.
It is currently being evaluated in a phase I/II study (NCT04278144) in patients with solid tumors, including breast, gastroesophageal, and colorectal that are HER2+ or HER2-low. The study is being conducted in four parts, with dose-escalation and dose-expansion parts exploring both monotherapy and combination with a PD-1 checkpoint inhibitor. Bristol Myers will provide Opdivo for the combination dose-escalation and combination dose-expansion portions of the trial. Bolt is the study sponsor and will be responsible for costs associated with the trial execution. The combination dose-escalation is expected to start later in the year.
Best Tech Stocks To Buy For 2022: GlobalSCAPE, Inc.(GSB)
GlobalSCAPE, Inc., incorporated on April 17, 1996, provides secure information exchange capabilities for enterprises and consumers through the development and distribution of software, delivery of managed and hosted solutions, and provisioning of associated services. The Company’s solution portfolio facilitates transmission of critical information, such as financial data, medical records, customer files, vendor files, personnel files, transaction activity and other similar documents between diverse and geographically separated network infrastructures. In addition to enabling secure transmission of critical information using servers, desktop and notebook computers, and a range of network-enabled mobile devices, its products also provide customers with the ability to monitor and audit file transfer activities. Its primary product is Enhance File Transfer (EFT).
The Company’s solution portfolio addresses data and information management, movement, security and accessibility across a range of environments encompassing data and information in motion and at rest. Its solutions also provide data replication, acceleration of file transfer, sharing/collaboration and continuous data backup, and recovery to its customers. Its software products and services include Managed File Transfer Solutions (MFT), Secure Content Mobility Solutions, Wide Area File Services (WAFS), Managed E-Mail Attachment Solution, Consumer-Based File Transfer Solution and professional services.
Managed File Transfer Solutions
The Company’s MFT products and solutions allow customers to move files and numbers of files securely. It facilitates management, monitoring, and reporting on the file transfers and deliver advanced workflow capabilities to move data and information into, out of, and throughout an enterprise. Its EFT solutions are server side solutions that provide a common MFT platform that accommodates a family of add-on modules to provide small and medium-sized businesses (SMBs), as well as larg! er enterprise customers, with security and automation file transfer protocol (FTP)-based and e-mail delivery systems. The add-on modules allow customers to select the solution configuration applicable to their requirements for auditing and reporting, encryption, ad hoc and Web-based file transfers, operability in or through a demilitarized zone (DMZ) network, and integration with back-end business processes, including workflow automation capabilities.
Secure Content Mobility Solutions
The Company’s secure content mobility solutions provide the ability to securely connect to and share documents, pictures, videos and music anytime, anywhere while minimizing the storage of data in the cloud and the associated security and privacy concerns. From the office, at home, or on the road, customers can connect to and access their files, stored in various locations, using any Web browser and most Internet-enabled tablets, smartphones and similar mobile devices. With these solutions, users can minimize uploading and/or synchronizing to a cloud storage location.
The Company’s scConnect is on-premises, enterprise file synchronization and sharing solution. It provides users with secure content mobility and the ability to share and access data anytime on any device. At the same time, scConnect provides information technology (IT) department administrators with the tools necessary to maintain the security of sensitive enterprise information and to control and monitor user access and activity. Its scConnect enables secure collaboration and content mobility without involving third-party servers. Secure content mobility integrates aspects of ad hoc file transfer, broader MFT capabilities, cloud services and remote accessibility. Its Wide-Area File Services (WAFS), software product uses data synchronization to replicate, share and backup files within a wide area network or local area network, thereby allowing users to access their data.
Wide Area File Services
! The Compa! ny’s WAFS software provides a file sharing, collaboration, and replication solution over multiple sites. WAFS technology provides enterprises with a file access and data protection combination that centralizes data storage and IT administration facilities without compromising data sharing and protection. A primary feature of WAFS is its byte-level differencing architecture that continually transmits only changed bytes (versus an entire file) thereby allowing update of files accessed by dispersed, multiple users. Other primary features of WAFS include native file locking, replication to multiple locations simultaneously and adherence to access control list files permissions, and UTF-8 support.
Managed E-mail Attachment Solution
The Company’s managed e-mail attachment solution, Mail Express, is a client-server application that allows users to send and receive e-mail attachments. Mail Express provides IT organizations by offering visibility into e-mail-based file movement across the enterprise, including tracking and auditing. The Mail Express application provides customer-defined administration privileges, which allow e-mail administrators and end users to configure specific parameters for handling e-mail attachments in accordance with corporate policy.
Consumer-Based File Transfer Solution
The Company’s CuteFTP is a client side software product, installed on a user’s local computer that enables file transfers from or to a file transfer server. The target market for the CuteFTP product includes corporate IT professionals using it to transfer data between locations through the Internet and individual Website operators using it to upload their Web pages to their Web hosting provider. Its CuteFTP Version 9 features include support for Unicode (UTF-8) characters, which allows for greater international use; Web Distributed Authoring and Versioning (WebDAV) support to facilitate collaboration between users in editing and managing documents and files stored on ! World Wid! e Web servers, and integration with TappIn, enabled by the WebDAV support.
The Company offers a range of professional services to complement its software and cloud-based solutions. These professional services include product customization and system integration, solution quickstart implementations, business process and workflow, policy development, education and training, and solution health checks. In addition, it provides longer-term engineering services, including supporting multi-year contracts.
The Company competes with Ipswitch, SolarWinds/Serv-U, JSCAPE, Axway, IBM-Sterling, Tibco, Van Dyke Software, Inc., Fetch Softworks, Interachry, Nolobe Software Pty Ltd, Panic, Inc., Panzura, Peer Sync, Riverbed Technology, Cisco, Accellion, Leapfile, Zix, Biscom, Thru, Inc. and Dropbox.
- [By Lisa Levin]
Check out these big penny stock gainers and losers
Akorn, Inc. (NASDAQ: AKRX) fell 32.7 percent to $13.25 in pre-market trading after Fresenius terminated its merger deal with Akorn.
Chicago Bridge & Iron Company N.V. (NYSE: CBI) fell 15.7 percent to $12.30 in pre-market trading. Subsea 7 confirmed a $7.00 per share proposal to acquire Mcdermott, pending termination of merger agreement with CB&I.
Myomo, Inc. (NYSE: MYO) fell 9 percent to $3.65 in pre-market trading after rising 11.39 percent on Friday.
Hasbro, Inc. (NASDAQ: HAS) fell 8 percent to $88.36 in pre-market trading after the company reported weaker-than-expected results for its first quarter on Monday.
SunPower Corporation (NASDAQ: SPWR) fell 7.1 percent to $9.00 in pre-market trading.
Endeavour Silver Corp. (NYSE: EXK) shares fell 5.9 percent to $2.88 in pre-market trading after declining 3.16 percent on Friday.
Mattel, Inc. (NASDAQ: MAT) shares fell 5.5 percent to $12.25 in pre-market trading.
Valeritas Holdings, Inc. (NASDAQ: VLRX) shares fell 5.1 percent to $2.96 in pre-market trading after rising 76.27 percent on Friday.
GlobalSCAPE, Inc. (NYSE: GSB) fell 5.1 percent to $3.57 in pre-market trading.
Fresenius Medical Care AG & Co. KGaA (NYSE: FMS) shares fell 4.1 percent to $49.93 in pre-market trading.
Oasis Petroleum Inc. (NYSE: OAS) fell 4.1 percent to $9.75 in pre-market trading. SunTrust Robinson Humphrey downgraded Oasis Petroleum from Hold to Sell
Best Tech Stocks To Buy For 2022: Flextronics International Ltd.(FLEX)
Flextronics International Ltd. provides design and electronics manufacturing services to original equipment manufacturers. The company offers its services to a range of products in the infrastructure, mobile communication devices, computing, consumer digital devices, industrial, semiconductor capital equipment, clean technology, aerospace and defense, white goods, automotive and marine, and medical devices markets. Its services include design and engineering services, such as contract design, joint development manufacturing, and original design and manufacturing services in a range of technical competencies that include system architecture, user interface and industrial design, mechanical engineering, enclosure systems, thermal and tooling design, electronic system design, reliability and failure analysis, and component level development engineering; and systems assembly and manufacturing services, including enclosures, testing, and materials procurement and inventory mana gement services. The company also offers various component product solutions comprising rigid and flexible printed circuit board fabrication, display and touch solutions, optomechatronics, and power supplies; after market supply chain logistics services; and reverse logistics and repair services, such as returns management, exchange programs, complex repair, asset recovery, recycling, and e-waste management services for consumer and midrange products, printers, PDA’s, mobile phones, consumer medical devices, notebooks, PC’s, set-top boxes, game consoles, and infrastructure products. It has operations in Asia, the Americas, and Europe. Flextronics International Ltd. was founded in 1990 and is headquartered in Singapore.
- [By Max Byerly]
United Services Automobile Association raised its stake in Flex Ltd (NASDAQ:FLEX) by 9.0% in the 2nd quarter, according to the company in its most recent filing with the Securities & Exchange Commission. The institutional investor owned 1,605,523 shares of the technology company’s stock after buying an additional 133,118 shares during the quarter. United Services Automobile Association owned approximately 0.30% of Flex worth $22,654,000 at the end of the most recent quarter.
- [By Ethan Ryder]
Get a free copy of the Zacks research report on Flex (FLEX)
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Best Tech Stocks To Buy For 2022: Lantronix, Inc.(LTRX)
Lantronix, Inc., incorporated on May 24, 2000, designs, develops, markets and sells networking and communications products with a focus on the convergence of mobility with machine-to-machine (M2M) systems. The Company provides solutions that enable machines, devices and sensors to be securely accessed, managed and controlled. The Companys solutions are designed for its customers to participate in the Internet of Things (IoT) market. The Company provides a portfolio of products intended for electronic devices or machines.
The Companys products are typically used by enterprise and commercial businesses, government institutions, telecommunication and utility companies, financial institutions, and individual consumers. The Company conducts its business globally and manages its sales teams by geography, according to four regions: the Americas; Europe, Middle East, and Africa (EMEA); Asia Pacific, and Japan. The Company has organized its solutions into two product lines based on how they are marketed, sold and deployed: OEM Modules and Enterprise Solutions.
OEM Modules are electronic products that serve as building blocks embedded inside electronic systems and equipment. The Companys OEM Modules product line includes wired and wireless products that are designed to for electronic systems and equipment by providing network connectivity, application hosting, protocol conversion and other functions. The products are offered with a software suite. Among others, product families included in the Companys OEM Module product line are MatchPort, PremiereWave EN, WiPort, xPico, xPico Wi-Fi and xPort.
The Companys Enterprise Solutions are electronic products that are typically connected to one or more existing pieces of electronic equipment to provide additional connectivity or functionality. The Enterprise Solutions are designed for machines and other devices through network connectivity, routing, switchin! g, application hosting, remote management, telemetry, telematics, printing, protocol conversion and other functions. The Companys Enterprise Solutions includes products such as wired and wireless device servers, I/O servers, terminal servers, console servers, print servers, remote keyboard video mouse (KVM), management, power management and software management platforms. Among others, product families included in the Companys Enterprise Solutions product line are EDS, PremierWave XC, PremierWave XN, SLB, SLC, SLP, Spider, UDS, xDirect, xPress, xPrintServer, and xSenso.
- [By Joseph Griffin]
Lantronix (NASDAQ:LTRX) was upgraded by equities research analysts at ValuEngine from a “hold” rating to a “buy” rating in a research note issued to investors on Thursday.
- [By Joseph Griffin]
Lantronix Inc (NASDAQ:LTRX)’s share price reached a new 52-week high during trading on Monday . The stock traded as high as $4.03 and last traded at $3.90, with a volume of 768 shares trading hands. The stock had previously closed at $3.85.
Best Tech Stocks To Buy For 2022: Silicon Laboratories Inc.(SLAB)
Silicon Laboratories Inc., a fabless semiconductor company, designs, develops, and markets analog-intensive and mixed-signal integrated circuits (ICs). The company offers broad-based products, which include microcontrollers, clocks and oscillators, wireless transceivers, digital isolators and related products, and human interface sensors and controllers; broadcast products comprising radio receivers and transmitters, and video tuners and demodulators; and access products consisting of embedded modems, subscriber line interface circuits, Voice over IP (VoIP) products, and power over Ethernet devices, as well as DSL analog front end ICs and IRDA devices. It provides ICs for use in various electronic applications, such as portable devices, AM/FM radios, and other consumer electronics, as well as networking, test and measurement, industrial monitoring and control, and customer premises equipment. The company markets its products through direct sales force, and through a networ k of independent sales representatives and distributors in the United States, Taiwan, China, South Korea, Japan, and internationally. Silicon Laboratories Inc. was founded in 1996 and is headquartered in Austin, Texas.
- [By Stephan Byrd]
Silicon Laboratories (NASDAQ:SLAB) has received an average rating of “Hold” from the thirteen brokerages that are presently covering the stock, Marketbeat Ratings reports. Eight equities research analysts have rated the stock with a hold rating and five have given a buy rating to the company. The average 1 year price objective among brokers that have issued ratings on the stock in the last year is $99.38.
- [By Logan Wallace]
Get a free copy of the Zacks research report on Silicon Laboratories (SLAB)
For more information about research offerings from Zacks Investment Research, visit Zacks.com
- [By Stephan Byrd]
Metropolitan Life Insurance Co. NY boosted its holdings in Silicon Laboratories (NASDAQ:SLAB) by 2.6% during the 2nd quarter, according to the company in its most recent filing with the Securities and Exchange Commission (SEC). The firm owned 25,100 shares of the semiconductor company’s stock after acquiring an additional 635 shares during the quarter. Metropolitan Life Insurance Co. NY owned 0.06% of Silicon Laboratories worth $2,500,000 at the end of the most recent quarter.
Best Tech Stocks To Buy For 2022: Glu Mobile Inc.(GLUU)
Glu Mobile Inc. designs, markets, and sells mobile games worldwide. It develops original games based on its intellectual property comprising Big Time Gangsta?, Blood & Glory, Bug Village, Contract Killer, Contract Killer: Zombies, Eternity Warriors, Frontline Commando, Gun Bros, Men vs. Machines, Stardom: The A-List, Super K.O. Boxing and Toyshop Adventures. The company also develops games based on licensed intellectual property consisting of Build-a-lot, Call of Duty, Deer Hunter, DJ Hero, Guitar Hero, Family Feud, Family Guy, Lord of the Rings, Paperboy, The Price Is Right, Transformers, Who Wants to Be a Millionaire?, and World Series of Poker. It offers a portfolio of action/adventure and casual games to smartphones and tablet devices users through direct-to-consumer digital storefronts, as well as to feature phone users served by wireless carriers and other distributors. The company was formerly known as Sorrent, Inc. and changed its name to Glu Mobile Inc. in May 20 05. Glu Mobile Inc. was incorporated in 2001 and is headquartered in San Francisco, California.
- [By ]
Glu Mobile (Nasdaq: GLUU) is a mobile game company that develops, publishes, and markets a portfolio of free-to-play mobile games for smartphones and tablet devices. GLUU specializes in four genres: home d茅cor, sports and action, fashion and celebrity, and time management, and creates games based on third-party licensed brands, such as Kim Kardashian: Hollywood, MLB Tap Sports Baseball, and Restaurant Dash with Gordon Ramsay. With expected growth of about 15% over the next few years, GLUU looks interesting, although its upside might be limited after the stock’s one-year 165% rally.
- [By ]
6. Glu Mobile (Nasdaq: GLUU) develops, publishes and markets a portfolio of free-to-play mobile games for smartphones and tablet devices. It primarily publishes titles in four genres, including home d茅cor, sports and action, fashion and celebrity, and time management. Some of its titled games are Contract Killer, Blood & Glory, Cooking Dash, Deer Hunter, QuizUp, and Tap Sports. The company pulled in $366 million in sales in 2018, a 28% increase over the previous year.
Best Tech Stocks To Buy For 2022: Taiwan Semiconductor Manufacturing Company Ltd.(TSM)
Taiwan Semiconductor Manufacturing Co., Ltd. (TSMC), incorporated on February 21, 1987, is a Taiwan-based company principally engaged in the manufacturing, selling, packaging, testing and computer-aided design of integrated circuits (ICs) and other semiconductor devices and the manufacturing of masks. The Company also offers a range of wafer fabrication processes, including processes to manufacture CMOS (complementary metal oxide silicon) logic, mixed-signal, radio frequency (RF), embedded memory, BiCMOS (bipolar complementary metal oxide silicon) mixed-signal and other semiconductors. It also offers design, mask making, bumping, probing, and assembly and testing services. TSMC operates one 150-millimeter wafer fab, six 200-millimeter wafer fabs and three 300-millimeter wafer fabs.
The Company manufactures different types of semiconductors with different specific functions by changing the number and the combinations of conducting, insulating and semiconducting layers and by defining different patterns in which such layers are applied on the wafer. At any given point in time, there are thousands of different products in various stages of fabrication at its fabs. The Company’s semiconductor types include logic semiconductors, mixed-signal/RF semiconductors and CMOS image sensor semiconductors.
Logic semiconductors process digital data to control the operation of electronic systems. Standard logic devices segment of the logic semiconductors market includes mobile computing chips, application processors, microcontrollers, digital signal processors (DSP), graphic chips and chipsets.
Analog/digital semiconductors combine analog and digital devices on a single semiconductor to process both analog and digital data. The Company makes mixed-signal/RF semiconductors using both the CMOS and BiCMOS processes. It offers CMOS mixed-signal process down to the 28-nanometer technology for manufacturing m! ixed-signal/RF semiconductors. The primary uses of mixed-signal/RF semiconductors are in hard disk drives, wireless communications equipment and network communications equipment, with those made with the BiCMOS process occupying the higher end of the mixed-signal/RF market.
CMOS Image Sensor Semiconductors
Image sensors are primarily used in camera phones and tablets. It produces CMOS image sensors, characterized by technology features, including low dark current, high sensitivity, small pixel size and high dynamic range achieved through integration with mixed mode processes.
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What direction the dollar takes from here remains to be seen, but whether the dollar goes up, down or sideways, having a little exposure to high-potential emerging markets can help round out the growth portion of your portfolio. Baron Emerging Markets one of the Kiplinger 25, a list of our favorite no-load funds owns some of the most exciting growth names in the developing world. It counts Taiwan Semiconductor (TSM), Alibaba Group (BABA) and Samsung among its largest holdings.
- [By Will Ashworth]
Sea is the largest holding in the fund with a weighting of 9.4%. Not surprisingly, MercadoLibre is the second-largest holding at 7.9%. I’ll be sure to pay closer attention to Sea in the future.
Stocks to Buy: Taiwan Semiconductor Manufacturing (TSM)
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And thats just the auto industry. The longer the chip shortage goes on, the more prices will rise in all types of products. That will benefit chip makers such as Intel (INTC) and Taiwan Semiconductor Manufacturing (TSM). Wall Street sees upside in the latter. Some two-thirds of analysts covering the stock rate it Buy, and the average price target implies about a 33% upside.